Difference between revisions of "Sr1"
| Line 137: | Line 137: | ||
<pubmed>16164558 17020585 17576690, </pubmed> | <pubmed>16164558 17020585 17576690, </pubmed> | ||
| − | |||
| − | |||
| − | |||
Revision as of 01:53, 16 June 2009
- Description: small regulatory RNA controlling AhrC expression
| Gene name | sr1 |
| Synonyms | ykzW |
| Essential | no |
| Product | small regulatory RNA/ regulatory peptide |
| Function | control of arginine metabolism |
| MW, pI | 4.4 kDa, 3.89 |
| Gene length, protein length | 205 bp (RNA), 120 bp (ORF), 39 aa |
| Immediate neighbours | slp, speA |
| Gene sequence | |
Genetic context 
| |
Contents
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
Additional information
Located between the slp and speA genes.
The RNA
Basic information/ Evolution
- Catalyzed reaction/ biological activity: hybridizes to ahrC mRNA and inhibits AhrC translation. PubMed
Extended information on the RNA
- Kinetic information
- Localization
Database entries
- Structure:
Additional information
Information on the structure of the RNA can be found in Heidrich et al., 2006
The peptide
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: the peptide is conserved in bacilli
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry:
- E.C. number:
Additional information
Expression and regulation
- Operon: sr1 PubMed
- Regulatory mechanism: transcription repression PubMed
- Additional information:
Biological materials
- Mutant: 168 sr1::cat, available in Brantl lab
- Expression vector:
- lacZ fusion:
Labs working on this gene/protein
Sabine Brantl, Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany homepage
Your additional remarks
References
Nadja Heidrich, Isabella Moll, Sabine Brantl
In vitro analysis of the interaction between the small RNA SR1 and its primary target ahrC mRNA.
Nucleic Acids Res: 2007, 35(13);4331-46
[PubMed:17576690]
[WorldCat.org]
[DOI]
(I p)
Nadja Heidrich, Alberto Chinali, Ulf Gerth, Sabine Brantl
The small untranslated RNA SR1 from the Bacillus subtilis genome is involved in the regulation of arginine catabolism.
Mol Microbiol: 2006, 62(2);520-36
[PubMed:17020585]
[WorldCat.org]
[DOI]
(P p)
Andreas Licht, Sven Preis, Sabine Brantl
Implication of CcpN in the regulation of a novel untranslated RNA (SR1) in Bacillus subtilis.
Mol Microbiol: 2005, 58(1);189-206
[PubMed:16164558]
[WorldCat.org]
[DOI]
(P p)
