Difference between revisions of "RasP"

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* '''Description:''' protease, cleaves RsiW upon alkaline shock <br/><br/>
+
* '''Description:''' intramembrane protease, cleaves [[RsiW]] upon alkaline shock <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || RsiW protease  
+
|style="background:#ABCDEF;" align="center"| '''Product''' || intramembrane [[RsiW]] protease  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of SigW activity
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigW]] activity
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 5.14   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 5.14   
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' cleaves [[RsiW]] upon alkaline shock
  
 
* '''Protein family:''' peptidase M50B family (according to Swiss-Prot)
 
* '''Protein family:''' peptidase M50B family (according to Swiss-Prot)
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* '''Interactions:''' [[RasP]]-[[FtsL]],  [[RasP]]-[[RsiW]]
 
* '''Interactions:''' [[RasP]]-[[FtsL]],  [[RasP]]-[[RsiW]]
  
* '''Localization:''' cell membrane (according to Swiss-Prot),  membrane associated [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
+
* '''Localization:''' cell membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 17:04, 7 June 2009

  • Description: intramembrane protease, cleaves RsiW upon alkaline shock

Gene name rasP
Synonyms yluC
Essential no
Product intramembrane RsiW protease
Function control of SigW activity
MW, pI 46 kDa, 5.14
Gene length, protein length 1266 bp, 422 aa
Immediate neighbours ispC, proS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YluC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU16560

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: cleaves RsiW upon alkaline shock
  • Protein family: peptidase M50B family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Thomas Wiegert, University of Bayreuth, Germany Homepage

Your additional remarks

References

  1. Hahne et al. (2008) From complementarity to comprehensiveness - targeting the membrane proteome of growing Bacillus subtilis by divergent approaches. Proteomics 8: 4123-4136 PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed