Difference between revisions of "TrpE"
(→References) |
|||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[trpE]]-[[trpD]]-[[trpC]]-[[trpF]]-[[trpB]]-[[trpA]]'' | + | * '''Operon:''' ''[[trpE]]-[[trpD]]-[[trpC]]-[[trpF]]-[[trpB]]-[[trpA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/3924737 PubMed] |
| − | * '''[[Sigma factor]]:''' [[SigA]] | + | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/6436812 PubMed] |
* '''Regulation:''' induction by tryptophan ([[MtrB| TRAP]]) | * '''Regulation:''' induction by tryptophan ([[MtrB| TRAP]]) | ||
| Line 118: | Line 118: | ||
=References= | =References= | ||
| − | <pubmed> 14976255 </pubmed> | + | <pubmed> 14976255, 3924737, 6436812 </pubmed> |
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed] | # Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed] | ||
Revision as of 17:27, 27 May 2009
- Description: anthranilate synthase
| Gene name | trpE |
| Synonyms | |
| Essential | no |
| Product | anthranilate synthase |
| Function | biosynthesis of tryptophan |
| MW, pI | 57 kDa, 5.246 |
| Gene length, protein length | 1545 bp, 515 aa |
| Immediate neighbours | trpD, aroH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P03963
- KEGG entry: BSU22680
- E.C. number: 4.1.3.27
Additional information
Expression and regulation
- Regulation: induction by tryptophan ( TRAP)
- Regulatory mechanism: TRAP: binding to the mRNA in the presence of tryptophan, this results in transcription termination
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
