ArgC

• Description: N-acetyl-g-glutamyl-phosphate reductase
  
  

Gene name	argC
Synonyms
Essential	no
Product	N-acetyl-g-glutamyl-phosphate reductase
Function	biosynthesis of arginine
MW, pI	37 kDa, 5.167
Gene length, protein length	1038 bp, 346 aa
Immediate neighbours	yitZ, argJ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: N-acetyl-L-glutamate 5-semialdehyde + NADP⁺ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH (according to Swiss-Prot)

• Protein family: Type 1 subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: P23715

• KEGG entry: BSU11190

• E.C. number: 1.2.1.38

Expression and regulation

• Operon: argC-argJ-argB-argD-carA-carB-argF

• Sigma factor: SigA

• Regulation: repressed by casamino acids PubMed, repressed by arginine (ArgR)

• Regulatory mechanism: ArgR: transcription repression

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Mäder et al. (2002) Transcriptome and Proteome Analysis of Bacillus subtilis Gene Expression Modulated by Amino Acid Availability. J. Bacteriol 184: 1844288-4295 PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed