Difference between revisions of "Sandbox"

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* '''Description:''' cadmium transporting ATPase, resistance to cadmium <br/><br/>
+
* '''Description:''' copper-transporting ATPase, resistance to copper <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''cadA''
+
|''copA''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvgW ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvgX ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || cadmium transporting ATPase  
+
|style="background:#ABCDEF;" align="center"| '''Product''' || copper transporting ATPase  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || cadmium export
+
|style="background:#ABCDEF;" align="center"|'''Function''' || copper export
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 75 kDa, 5.998  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 85 kDa, 5.484  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2106 bp, 702 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2409 bp, 803 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[bdbD]]'', ''[[copA]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cadA]]'', ''[[copZ]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15354&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15355&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|-
 
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:yvgW_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:yvgX_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
Line 43: Line 43:
 
* '''DBTBS entry:''' no entry
 
* '''DBTBS entry:''' no entry
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG14105]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG14106]
  
 
=== Additional information===
 
=== Additional information===
Line 52: Line 52:
 
=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' ATP + H<sub>2</sub>O + Cd<sup>2+</sup>(In) = ADP + phosphate + Cd<sup>2+</sup>(Out)  
+
* '''Catalyzed reaction/ biological activity:''' ATP + H<sub>2</sub>O + Cu<sup>1+</sup>(In) = ADP + phosphate + Cu<sup>1+</sup>(Out)  
  
 
* '''Protein family:''' Type IB subfamily (according to Swiss-Prot)
 
* '''Protein family:''' Type IB subfamily (according to Swiss-Prot)
Line 70: Line 70:
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''Interactions:''' [[CopA]]-[[CopZ]]
  
 
* '''Localization:''' cell membrane (according to Swiss-Prot)
 
* '''Localization:''' cell membrane (according to Swiss-Prot)
Line 76: Line 76:
 
=== Database entries ===
 
=== Database entries ===
  
* '''Structure:'''
+
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2RML 2RML] ( N-terminal soluble domain)
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O32219 O32219]
+
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O32220 O32220]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU33490 BSU33490]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU33500 BSU33500]
  
* '''E.C. number:''' [http://www.expasy.org/enzyme/3.6.3.3 3.6.3.3]
+
* '''E.C. number:'''
  
 
=== Additional information===
 
=== Additional information===
Line 118: Line 118:
 
=References=
 
=References=
  
 +
<pubmed> 19378562  </pubmed>
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]

Revision as of 01:47, 23 May 2009

  • Description: copper-transporting ATPase, resistance to copper

Gene name copA
Synonyms yvgX
Essential no
Product copper transporting ATPase
Function copper export
MW, pI 85 kDa, 5.484
Gene length, protein length 2409 bp, 803 aa
Immediate neighbours cadA, copZ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvgX context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + H2O + Cu1+(In) = ADP + phosphate + Cu1+(Out)
  • Protein family: Type IB subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure: 2RML ( N-terminal soluble domain)
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed