LicR

• Description: transcriptional activator of the licB-licC-licA-licH operon
  
  

Gene name	licR
Synonyms	celR
Essential	no
Product	transcriptional activator (PRD type)
Function	regulation of lichenan utilization
MW, pI	73 kDa, 6.115
Gene length, protein length	1923 bp, 641 aa
Immediate neighbours	licB, yxzF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)

• Protein family: transcriptional antiterminator bglG family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: LicB-LicR, PtsH-LicR

• Localization:

Database entries

• Structure:

• Swiss prot entry: P46321

• KEGG entry: BSU38600

• E.C. number: 2.7.1.69

Expression and regulation

• Operon:

• Sigma factor: sigB PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Tobisch, S., P. Glaser, S. Krüger, and M. Hecker. 1997. Identification and characterization of a new ß-glucoside utilization system in Bacillus subtilis. J. Bacteriol. 179:496-506. PubMed
2. Tobisch, S., Stülke, J., & Hecker, M. (1999) Regulation of the lic operon of Bacillus subtilis and characterization of potential phosphorylation sites of the LicR regulator protein by site-directed mutagenesis. J. Bacteriol. 181: 4995-5003. PubMed
3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed