PyrD

• Description: dihydoorotic acid dehydrogenase (catalytic subunit)
  
  

Gene name	pyrD
Synonyms	pyrDI
Essential	no
Product	dihydoorotic acid dehydrogenase (catalytic subunit)
Function	pyrimidine biosynthesis
MW, pI	32 kDa, 4.942
Gene length, protein length	933 bp, 311 aa
Immediate neighbours	pyrK, pyrF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: (S)-dihydroorotate + O₂ = orotate + H₂O₂ (according to Swiss-Prot)

• Protein family: Type 1 subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: P25996

• KEGG entry: BSU15540

• E.C. number: 1.3.3.1

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed