GutR

• Description: transcription activator of the gutB-gutP operon
  
  

Gene name	gutR
Synonyms
Essential	no
Product	transcription activator
Function	regulation of glucitol utilization
MW, pI	94 kDa, 6.113
Gene length, protein length	2487 bp, 829 aa
Immediate neighbours	ydjC, gutB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: P39143

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Ye R, Rehemtulla SN, Wong SL. (1994) Glucitol induction in Bacillus subtilis is mediated by a regulatory factor, GutR. J Bacteriol. Jun;176(11): 3321-7. PubMed
2. Ye R, Wong SL. (1994) Transcriptional regulation of the Bacillus subtilis glucitol dehydrogenase gene. J Bacteriol. Jun;176(11): 3314-20. PubMed
3. Poon KK, Chen CL, Wong SL. (2001) Roles of glucitol in the GutR-mediated transcription activation process in Bacillus subtilis: tight binding of GutR to tis binding site. J Biol Chem. Mar 30;276(13): 9620-5 PubMed