YkuI

• Description: c-di-GMP specific phosphodiesterase
  
  

Gene name	ykuI
Synonyms
Essential	no
Product	c-di-GMP specific phosphodiesterase
Function	unknown
MW, pI	47 kDa, 4.462
Gene length, protein length	1221 bp, 407 aa
Immediate neighbours	ykuH, fsrA
Gene sequence (+200bp)	Protein sequence
Genetic context

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: degradation of cyclic di-GMP PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: EAL domain (aa 1 ... 245, for c-di-GMP hydrolysis), PAS-like domain (aa 300 ... 400) PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2BAS, in complex with c-di-GMP 2W27 PubMed

• Swiss prot entry:

• KEGG entry:

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Minasov et al. (2009) Crystal structures of YkuI and its complex with second messenger c-di-GMP suggests catalytic mechanism of phosphodiester bond cleavage by EAL domains J. Biol. Chem volume: page-page. PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed