Difference between revisions of "NagR"

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(References)
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* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU35030&redirect=T BSU35030]
 
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU35030&redirect=T BSU35030]
  
* '''Structure:''' [http://www.rcsb.org/pdb/search/structidSearch.do?structureId=2WV0 2WVO] {{PubMed|20047956}}
+
* '''Structure:'''  
 +
** [http://www.rcsb.org/pdb/search/structidSearch.do?structureId=2WV0 2WVO] {{PubMed|20047956}}
 +
** [http://www.rcsb.org/pdb/explore/explore.do?structureId=4wwc 4WWC] (complex with palindromic operator DNA) {{PubMed|25564531}}
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34817 O34817]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34817 O34817]

Revision as of 16:41, 16 February 2015

Gene name nagR
Synonyms yvoA
Essential no
Product transcriptional regulator (GntR family)
Function probably regulator of the putative nagA-nagB-yvoA operon
Gene expression levels in SubtiExpress: nagR
Metabolic function and regulation of this protein in SubtiPathways:
nagR
MW, pI 27 kDa, 6.768
Gene length, protein length 729 bp, 243 aa
Immediate neighbours nagB, yvnB
Sequences Protein DNA DNA_with_flanks
Genetic context
YvoA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NagR expression.png















Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

NagR regulon

The NagR regulon:

The gene

Basic information

  • Locus tag: BSU35030

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription repression of nagP and of the putative nagA-nagB-nagR operon in the absence of N-acetylglycosamine PubMed, weak repression of yflG PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information: K(D) for N-acetylglucosamine-6-phosphate: 1 mM PubMed
  • Modification:
  • Effectors of protein activity:
    • N-acetylglucosamine-6-phosphate and glucosamine-6-phosphate act as the molecular inducers PubMed

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced in the presence of N-acetylglucosamine (NagR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References