TetB

• Description: multifunctional tetracycline/Na+ resistance protein
  
  

Gene name	tetB
Synonyms	tetA, tetA(L)
Essential	no
Product	multifunctional tetracycline/Na+ resistance protein
Function	resistance to tetracyclin
Gene expression levels in SubtiExpress: tetB
MW, pI	49 kDa, 9.537
Gene length, protein length	1374 bp, 458 aa
Immediate neighbours	yyaP, tetL
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, resistance against toxins/ antibiotics, membrane proteins

The gene

Basic information

• Locus tag: BSU40770

Database entries

• BsubCyc: BSU40770

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: TCR/tet family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU40770

• Structure:

• UniProt: P23054

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: tetL-tetB (according to DBTBS)

• Expression browser: tetB PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • GP2080 (tetB::cat), available in Jörg Stülke's lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

David Bechhofer, Mount Sinai School, New York, USA Homepage