MhqA

• Description: hydroquinone-specific dioxygenase, confers resistence to methyl-hydroxyquinone
  
  

Gene name	mhqA
Synonyms	ykcA
Essential	no
Product	hydroquinone-specific dioxygenase
Function	resistence to methyl-hydroxyquinone
Gene expression levels in SubtiExpress: mhqA
MW, pI	35 kDa, 5.404
Gene length, protein length	948 bp, 316 aa
Immediate neighbours	steT, ykcB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

MhqR regulon

The gene

Basic information

• Locus tag: BSU12870

Database entries

• BsubCyc: BSU12870

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: extradiol ring-cleavage dioxygenase family (according to UniProt)

• Paralogous protein(s): MhqE, MhqO

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU12870

• Structure: 3OAJ (MhqO, 34% identical residues)

• UniProt: O34689

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: mhqA PubMed

• Expression browser: mhqA PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by catechol and 2-methylhydroquinone (MhqR) PubMed

• Regulatory mechanism:
  • MhqR: transcription repression PubMed

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 183 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: