Difference between revisions of "SpsJ"

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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigE regulon]]}},
+
{{SubtiWiki regulon|[[GerE regulon]]}},
 
{{SubtiWiki regulon|[[SigK regulon]]}}
 
{{SubtiWiki regulon|[[SigK regulon]]}}
  
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spsJ_3884292_3885239_-1 spsJ] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spsJ_3884292_3885239_-1 spsJ] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigK]] {{PubMed|15383836}}  
+
* '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15383836}}  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** expressed late during sporulation in the mother cell ([[SigK]]) {{PubMed|15383836}}  
+
** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|25239894,15383836}}  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[GerE]]: transcription activation {{PubMed|25239894,15383836}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
<pubmed>9353933 15383836 22960854 </pubmed>
+
<pubmed>9353933 15383836 22960854 25239894</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:35, 23 September 2014

  • Description: dTDP -glucose-4,6-dehydratase, spore coat polysaccharide synthesis

Gene name spsJ
Synonyms ipa-72d
Essential no
Product dTDP -glucose-4,6-dehydratase
Function rhamnose biosynthesis, spore coat polysaccharide synthesis
Gene expression levels in SubtiExpress: spsJ
MW, pI 35 kDa, 6.286
Gene length, protein length 945 bp, 315 aa
Immediate neighbours spsK, spsI
Sequences Protein DNA DNA_with_flanks
Genetic context
SpsJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpsJ expression.png















Categories containing this gene/protein

miscellaneous metabolic pathways, sporulation proteins

This gene is a member of the following regulons

GerE regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU37830

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • dTDP-glucose --> dTDP-4-dehydro-6-deoxyglucose PubMed
  • Protein family: sugar epimerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References