AzoR2

• Description: similar to NAD(P)H dehydrogenase (quinone)
  
  

Gene name	azoR2
Synonyms	yvaB
Essential	no
Product	azoreductase
Function	resistance to 2-methylhydroquinone
Gene expression levels in SubtiExpress: azoR2
MW, pI	23 kDa, 5.114
Gene length, protein length	633 bp, 211 aa
Immediate neighbours	yvaA, yvaC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

MhqR regulon, SigG regulon

The gene

Basic information

• Locus tag: BSU33540

Database entries

• BsubCyc: BSU33540

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: azoreductase type 1 family (according to Swiss-Prot)

• Paralogous protein(s): AzoR1

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU33540

• Structure: 3P0R (from B. anthracis, 43% identity, 61% similarity)

• UniProt: O32224

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: azoR2 PubMed

• Expression browser: azoR2 PubMed

• Sigma factor: SigA PubMed, SigG PubMed

• Regulation:
  • induced by catechol and 2-methylhydroquinone (2-MHQ) (MhqR) PubMed
  • repressed by casamino acids PubMed

• Regulatory mechanism:
  • MhqR: transcription repression PubMed

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 1516 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1290 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: