Difference between revisions of "LiaI"

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* '''Description:''' resistance against oxidative stress and cell wall antibiotics, may act as membrane anchor for [[LiaH]] <br/><br/>
+
* '''Description:''' resistance against oxidative stress and cell wall antibiotics, membrane anchor for [[LiaH]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
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|style="background:#ABCDEF;" align="center"| '''Product''' || membrane anchor for [[LiaH]] 
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance against oxidative stress and cell wall antibiotics
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance against oxidative stress and cell wall antibiotics
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 +
** [[LiaI]]-[[LiaH]] {{PubMed|24666271}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
** cell membrane (according to Swiss-Prot)
+
** cell membrane {{PubMed|24666271}}
 +
** forms highly dynamic membrane-associated foci under non-inducing conditions {{PubMed|24666271}}
 +
** co-localizes with [[LiaH]] in distinct static spots at the cytoplasma membrane under stress conditions {{PubMed|24666271}}
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
<pubmed>19164152,15273097,17660417,17600057,20057163 ,16816187,15101989,17660417,12850135 16816187, 20639339 20817675 ,22092710</pubmed>
+
<pubmed>19164152,15273097,17660417,17600057,20057163 ,16816187,15101989,17660417,12850135 16816187, 20639339 20817675 ,22092710 24666271 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:09, 10 October 2014

  • Description: resistance against oxidative stress and cell wall antibiotics, membrane anchor for LiaH

Gene name liaI
Synonyms yvqI
Essential no
Product membrane anchor for LiaH
Function resistance against oxidative stress and cell wall antibiotics
Gene expression levels in SubtiExpress: liaI
MW, pI 13 kDa, 9.303
Gene length, protein length 378 bp, 126 aa
Immediate neighbours liaH, yvqJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YvqI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LiaI expression.png















Categories containing this gene/protein

resistance against oxidative and electrophile stress, resistance against toxins/ antibiotics, membrane proteins

This gene is a member of the following regulons

LiaR regulon

The gene

Basic information

  • Locus tag: BSU33130

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • cell membrane PubMed
    • forms highly dynamic membrane-associated foci under non-inducing conditions PubMed
    • co-localizes with LiaH in distinct static spots at the cytoplasma membrane under stress conditions PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References