Difference between revisions of "FliR"

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* '''Description:''' flagellar protein required for flagellar formation <br/><br/>
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* '''Description:''' part of the flagellar type III export apparatus <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || flagellar protein required for flagellar formation
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|style="background:#ABCDEF;" align="center"| '''Product''' || part of the flagellar type III export apparatus
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || movement and chemotaxis
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|style="background:#ABCDEF;" align="center"|'''Function''' || export of flagellum components
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16370 fliR]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16370 fliR]
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
 
{{SubtiWiki category|[[motility and chemotaxis]]}},
 
{{SubtiWiki category|[[motility and chemotaxis]]}},
 +
{{SubtiWiki category|[[protein secretion]]}},
 
{{SubtiWiki category|[[membrane proteins]]}}
 
{{SubtiWiki category|[[membrane proteins]]}}
  
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* no secretion of [[FlgM]], permanent inhibition of [[SigD]] {{PubMed|25313396}}
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
  
<pubmed>8299954,17850253,14651647,9657996,8157612,15175317 21821766</pubmed>
+
<pubmed>8299954,17850253,14651647,9657996,8157612,15175317 21821766 25313396</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:14, 27 October 2014

  • Description: part of the flagellar type III export apparatus

Gene name fliR
Synonyms
Essential no
Product part of the flagellar type III export apparatus
Function export of flagellum components
Gene expression levels in SubtiExpress: fliR
MW, pI 28 kDa, 5.582
Gene length, protein length 777 bp, 259 aa
Immediate neighbours fliQ, flhB
Sequences Protein DNA DNA_with_flanks
Genetic context
FliR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FliR expression.png















Categories containing this gene/protein

motility and chemotaxis, protein secretion, membrane proteins

This gene is a member of the following regulons

CodY regulon, SigD regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU16370

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

  • A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: fliR/mopE/spaR family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References