Difference between revisions of "FliL"

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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
{{SubtiWiki regulon|[[CodY regulon]]}},
 
{{SubtiWiki regulon|[[CodY regulon]]}},
 +
{{SubtiWiki regulon|[[DegU regulon]]}},
 
{{SubtiWiki regulon|[[SigD regulon]]}},
 
{{SubtiWiki regulon|[[SigD regulon]]}},
 
{{SubtiWiki regulon|[[Spo0A regulon]]}}
 
{{SubtiWiki regulon|[[Spo0A regulon]]}}
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** ''[[flgB]]'': [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}}
 
** ''[[flgB]]'': [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}}
 
** ''[[ylxF]]'': [[SigD]] {{PubMed|20233303}}
 
** ''[[ylxF]]'': [[SigD]] {{PubMed|20233303}}
** [[DegU]] (non-phosphorylated): transcription activation {{PubMed|17850253}}
+
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
Line 122: Line 123:
 
** [[Spo0A]]: transcription repression {{PubMed|14651647}}
 
** [[Spo0A]]: transcription repression {{PubMed|14651647}}
 
** [[CodY]]: transcription repression {{PubMed|12730172}}
 
** [[CodY]]: transcription repression {{PubMed|12730172}}
 +
** [[DegU]] (non-phosphorylated): transcription activation {{PubMed|17850253}}
 +
** [[DegU]]-P: transcription repression {{PubMed|24386445}}
 +
** [[DegU]]-P in complex with [[SwrA]]: transcription activation {{PubMed|24386445}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
  
<pubmed>14651647, 9657996,8157612,15175317 17850253 21821766</pubmed>
+
<pubmed>14651647, 9657996,8157612,15175317 17850253 21821766 24386445</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 15:43, 29 December 2014

  • Description: flagellar protein required for flagellar formation , membrane protein

Gene name fliL
Synonyms
Essential no
Product flagellar protein required for flagellar formation , membrane protein
Function movement and chemotaxis
Gene expression levels in SubtiExpress: fliL
MW, pI 15 kDa, 5.175
Gene length, protein length 420 bp, 140 aa
Immediate neighbours ylzI, fliM
Sequences Protein DNA DNA_with_flanks
Genetic context
FliL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FliL expression.png















Categories containing this gene/protein

motility and chemotaxis, membrane proteins

This gene is a member of the following regulons

CodY regulon, DegU regulon, SigD regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU16300

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

  • A mutation was found in this gene after evolution under relexed selection for sporulation PubMed


The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: fliL family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation


  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References