Difference between revisions of "LmrB"

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(Biological materials)
(Biological materials)
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* '''Mutant:'''
 
* '''Mutant:'''
** GP1701 (''lmrB''::''aphA3''), available in [[Jörg Stülke]]'s lab
+
** GP1701 (''[[lmrB]]''::''aphA3''), available in [[Jörg Stülke]]'s lab
** GP1703 (''lmrB''::''aphA3'' ''ycnB''::''spc''), available in [[Jörg Stülke]]'s lab
+
** GP1703 (''[[lmrB]]''::''aphA3'' ''[[ycnB]]''::''spc''), available in [[Jörg Stülke]]'s lab
 
* '''Expression vector:'''
 
* '''Expression vector:'''
 
          
 
          

Revision as of 11:57, 14 March 2014

  • Description: lincomycin-resistance protein (multidrug resistance pump)

Gene name lmrB
Synonyms yccA
Essential no
Product lincomycin-resistance protein
Function resistance to lincomycin
Gene expression levels in SubtiExpress: lmrB
MW, pI 51 kDa, 9.703
Gene length, protein length 1437 bp, 479 aa
Immediate neighbours ycbU, lmrA
Sequences Protein DNA DNA_with_flanks
Genetic context
LmrB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LmrB expression.png















Categories containing this gene/protein

transporters/ other, resistance against toxins/ antibiotics, membrane proteins

This gene is a member of the following regulons

LmrA regulon

The gene

Basic information

  • Locus tag: BSU02670

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: EmrB family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced by flavonoids such as quercetin (LmrA)PubMed
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is substantially stabilized upon depletion of RNase Y PubMed

Biological materials

  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References