Difference between revisions of "PurA"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU40420&redirect=T BSU40420] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/purA.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/purA.html] | ||
| Line 92: | Line 93: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU40420&redirect=T BSU40420] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KJX 1KJX] (from ''Escherichia coli k12'', 46% identity, 64% similarity) {{PubMed|11741996}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KJX 1KJX] (from ''Escherichia coli k12'', 46% identity, 64% similarity) {{PubMed|11741996}} | ||
Revision as of 15:16, 2 April 2014
- Description: adenylosuccinate synthetase
| Gene name | purA |
| Synonyms | |
| Essential | no |
| Product | adenylosuccinate synthetase |
| Function | purine biosynthesis |
| Gene expression levels in SubtiExpress: purA | |
| Metabolic function and regulation of this protein in SubtiPathways: purA | |
| MW, pI | 47 kDa, 5.459 |
| Gene length, protein length | 1290 bp, 430 aa |
| Immediate neighbours | trnY-Lys, yycE |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, phosphoproteins, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40420
Phenotypes of a mutant
Database entries
- BsubCyc: BSU40420
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)-AMP (according to Swiss-Prot)
- Protein family: adenylosuccinate synthetase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- phosphorylated on Arg-97 PubMed
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- BsubCyc: BSU40420
- UniProt: P29726
- KEGG entry: [3]
- E.C. number: 6.3.4.4
Additional information
Expression and regulation
- Operon: purA PubMed
- Additional information:
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
