Difference between revisions of "MetK"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30550&redirect=T BSU30550] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/metK.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/metK.html] | ||
| Line 92: | Line 93: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30550&redirect=T BSU30550] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FUG 1FUG] (from ''Escherichia coli'', 63% identity, 75% similarity) {{PubMed|8723769}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FUG 1FUG] (from ''Escherichia coli'', 63% identity, 75% similarity) {{PubMed|8723769}} | ||
Revision as of 14:34, 2 April 2014
- Description: S-adenosylmethionine synthetase
| Gene name | metK |
| Synonyms | metE |
| Essential | yes PubMed |
| Product | S-adenosylmethionine synthetase |
| Function | S-adenosylmethionine synthesis |
| Gene expression levels in SubtiExpress: metK | |
| Metabolic function and regulation of this protein in SubtiPathways: metK | |
| MW, pI | 43 kDa, 5.025 |
| Gene length, protein length | 1200 bp, 400 aa |
| Immediate neighbours | asnB, pckA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids, essential genes, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU30550
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU30550
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine (according to Swiss-Prot)
- Protein family: AdoMet synthetase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- BsubCyc: BSU30550
- UniProt: P54419
- KEGG entry: [3]
- E.C. number: 2.5.1.6
Additional information
Expression and regulation
- Regulatory mechanism:
- S-box: riboswitch, binds S-adenosylmethionine resulting in transcription termination PubMed
- Additional information:
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
