Difference between revisions of "WalR"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU40410&redirect=T BSU40410] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yycFGHIJ-yyxA.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yycFGHIJ-yyxA.html] | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU40410&redirect=T BSU40410] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2D1V 2D1V] (DNA binding domain), [http://www.rcsb.org/pdb/explore.do?structureId=2ZWM 2ZWM] (receiver domain) | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2D1V 2D1V] (DNA binding domain), [http://www.rcsb.org/pdb/explore.do?structureId=2ZWM 2ZWM] (receiver domain) | ||
Revision as of 15:16, 2 April 2014
- Description: two-component response regulator, controls cell wall metabolism
| Gene name | walR |
| Synonyms | yycF |
| Essential | yes PubMed |
| Product | two-component response regulator |
| Function | control of cell wall metabolism |
| Gene expression levels in SubtiExpress: walR | |
| Interactions involving this protein in SubtInteract: WalR | |
| MW, pI | 27 kDa, 4.876 |
| Gene length, protein length | 705 bp, 235 aa |
| Immediate neighbours | walK, trnY-Phe |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall/ other, transcription factors and their control, essential genes, phosphoproteins
This gene is a member of the following regulons
The WalR regulon
The gene
Basic information
- Locus tag: BSU40410
Phenotypes of a mutant
- essential PubMed
- a constitutively active form of WalR (WalR-R204C) results in constitutive expression of the WalR regulon, and in combination with a sepF mutation to the formation of cell wall-less L-forms PubMed
Database entries
- BsubCyc: BSU40410
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: OmpR family of two-component transcription regulators
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification: phosphorylated by WalK on an Asp residue
- Effectors of protein activity: phosphorylation likely affects DNA-binding activity
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- BsubCyc: BSU40410
- UniProt: P37478
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Kevin Devine, Dublin
Your additional remarks
References
Reviews
The WalR regulon
Other original Publications
