Difference between revisions of "RecD2"
(→Categories containing this gene/protein) |
|||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || 5'-3' DNA helicase |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || replication fork progression |
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27480 | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27480 RecD2] |
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=YrrC | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=YrrC RecD2] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 88 kDa, 5.08 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 88 kDa, 5.08 | ||
| Line 37: | Line 37: | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
| − | |||
| − | |||
| − | |||
| − | |||
<br/><br/> | <br/><br/> | ||
| Line 56: | Line 52: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * modest increase in spontaneous mutation rate {{PubMed|24443534}} | ||
=== Database entries === | === Database entries === | ||
| Line 79: | Line 76: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| − | ** [[SsbA]]-[[ | + | ** [[SsbA]]-[[RecD2]] {{PubMed|21170359}} |
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| Line 108: | Line 105: | ||
* '''Operon:''' | * '''Operon:''' | ||
| − | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yrrC_2806286_2808682_-1 | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yrrC_2806286_2808682_-1 recD2] {{PubMed|22383849}} |
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 137: | Line 134: | ||
=References= | =References= | ||
| − | + | <pubmed> 21170359 24443534 </pubmed> | |
| + | |||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:13, 21 January 2014
- Description: similar to exodeoxyribonuclease V alpha subunit
| Gene name | yrrC |
| Synonyms | |
| Essential | no |
| Product | 5'-3' DNA helicase |
| Function | replication fork progression |
| Gene expression levels in SubtiExpress: RecD2 | |
| Interactions involving this protein in SubtInteract: RecD2 | |
| MW, pI | 88 kDa, 5.08 |
| Gene length, protein length | 2394 bp, 798 aa |
| Immediate neighbours | yrrD, yrrB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27480
Phenotypes of a mutant
- modest increase in spontaneous mutation rate PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34481
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Brian W Walsh, Samantha A Bolz, Sarah R Wessel, Jeremy W Schroeder, James L Keck, Lyle A Simmons
RecD2 helicase limits replication fork stress in Bacillus subtilis.
J Bacteriol: 2014, 196(7);1359-68
[PubMed:24443534]
[WorldCat.org]
[DOI]
(I p)
Audrey Costes, François Lecointe, Stephen McGovern, Sophie Quevillon-Cheruel, Patrice Polard
The C-terminal domain of the bacterial SSB protein acts as a DNA maintenance hub at active chromosome replication forks.
PLoS Genet: 2010, 6(12);e1001238
[PubMed:21170359]
[WorldCat.org]
[DOI]
(I e)
