Difference between revisions of "ThrS"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[translation]]}} | + | {{SubtiWiki category|[[translation]]}}, |
| + | [[most abundant proteins]] | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:'''Cys573 is S-bacillithiolated by NaOCl stress [http://www.ncbi.nlm.nih.gov/sites/entrez/22938038 PubMed] | * '''Modification:'''Cys573 is S-bacillithiolated by NaOCl stress [http://www.ncbi.nlm.nih.gov/sites/entrez/22938038 PubMed] | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thrS_2959257_2961188_-1 thrS] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thrS_2959257_2961188_-1 thrS] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|8288542}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8288542}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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** [[T-box]]: [[RNA switch]], transcriptional antitermination {{PubMed|19258532}} | ** [[T-box]]: [[RNA switch]], transcriptional antitermination {{PubMed|19258532}} | ||
| − | * '''Additional information:''' subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+17981983 PubMed] | + | * '''Additional information:''' |
| + | ** subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+17981983 PubMed] | ||
| + | ** belongs to the 100 [[most abundant proteins]] {{PubMed|15378759}} | ||
=Biological materials = | =Biological materials = | ||
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=References= | =References= | ||
| − | <pubmed>22938038,8288542,1379177,19258532,7476165,12136084,8969504 ,17114254, 22848659</pubmed> | + | <pubmed>22938038,8288542,1379177,19258532,7476165,12136084,8969504 ,17114254, 22848659 15378759</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:56, 5 March 2014
- Description: threonyl-tRNA synthetase (major)
| Gene name | thrS |
| Synonyms | |
| Essential | no |
| Product | threonyl-tRNA synthetase (major) |
| Function | translation |
| Gene expression levels in SubtiExpress: thrS | |
| Metabolic function and regulation of this protein in SubtiPathways: thrS | |
| MW, pI | 73 kDa, 5.214 |
| Gene length, protein length | 1929 bp, 643 aa |
| Immediate neighbours | ysaA, ytxC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
translation, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28950
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr) (according to Swiss-Prot)
- Protein family: class-II aminoacyl-tRNA synthetase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Modification:Cys573 is S-bacillithiolated by NaOCl stress PubMed
- Effectors of protein activity:
Database entries
- UniProt: P18255
- KEGG entry: [3]
- E.C. number: 6.1.1.3
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Regulation:
- Regulatory mechanism:
- T-box: RNA switch, transcriptional antitermination PubMed
- Additional information:
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
