Difference between revisions of "DapB"
| Line 60: | Line 60: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU22490&redirect=T BSU22490] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
| Line 95: | Line 96: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU22490&redirect=T BSU22490] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1YL6 1YL6] (from ''Mycobacterium tuberculosis'', 46% identity, 67% similarity) {{PubMed|20057050}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1YL6 1YL6] (from ''Mycobacterium tuberculosis'', 46% identity, 67% similarity) {{PubMed|20057050}} | ||
Revision as of 14:03, 2 April 2014
- Description: dihydrodipicolinate reductase (NADPH)
| Gene name | dapB |
| Synonyms | |
| Essential | yes PubMed |
| Product | dihydrodipicolinate reductase (NADPH) |
| Function | biosynthesis of lysine and peptidoglycan |
| Gene expression levels in SubtiExpress: dapB | |
| Metabolic function and regulation of this protein in SubtiPathways: dapB | |
| MW, pI | 29 kDa, 5.057 |
| Gene length, protein length | 801 bp, 267 aa |
| Immediate neighbours | mgsA, ypjD |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis/ acquisition of amino acids, Biosynthesis of cell wall components, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22490
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU22490
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2,3,4,5-tetrahydrodipicolinate + NADP+ = 2,3-dihydrodipicolinate + NADPH (according to Swiss-Prot)
- Protein family: glucose-6-phosphate dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Cofactors: NADP+
- Effectors of protein activity:
- Interactions:
- forms tetramers PubMed
Database entries
- BsubCyc: BSU22490
- UniProt: P42976
- KEGG entry: [2]
- E.C. number: 1.3.1.26
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Operon and expression
