SigY

• Description: RNA polymerase ECF-type sigma factor SigY
  
  

Gene name	sigY
Synonyms	yxlB
Essential	no
Product	RNA polymerase ECF-type sigma factor SigY
Function	maintenance of the SPß prophage
Gene expression levels in SubtiExpress: sigY
Interactions involving this protein in SubtInteract: SigY
MW, pI	21 kDa, 9.549
Gene length, protein length	534 bp, 178 aa
Immediate neighbours	yxlC, yxlA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription, sigma factors and their control, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigY regulon

The gene

Basic information

• Locus tag: BSU38700

Phenotypes of a mutant

• loss of the SPß prophage PubMed
• sensitive to killing by sublancin PubMed
• no production of sublancin PubMed

Database entries

• BsubCyc: BSU38700

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ECF subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SigY-(RpoB-RpoC)
  • SigY- YxlC PubMed

• Localization:

Database entries

• BsubCyc: BSU38700

• Structure:

• UniProt: P94370

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sigY-yxlC-yxlD-yxlE-yxlF-yxlG PubMed

• Expression browser: sigY PubMed

• Sigma factor: SigY PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A909 ( sigY::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

The SigY regulon

Thorsten Mascher, Anna-Barbara Hachmann, John D Helmann
Regulatory overlap and functional redundancy among Bacillus subtilis extracytoplasmic function sigma factors.
J Bacteriol: 2007, 189(19);6919-27
[PubMed:17675383] [WorldCat.org] [DOI] (P p)

Other original publications

Additional publications: PubMed