YcbL

• Description: two-component response regulator
  
  

Gene name	ycbL
Synonyms
Essential	no
Product	two-component response regulator
Function	unknown
Gene expression levels in SubtiExpress: ycbL
Interactions involving this protein in SubtInteract: YcbL
MW, pI	25 kDa, 4.917
Gene length, protein length	678 bp, 226 aa
Immediate neighbours	ycbK, ycbM
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, phosphoproteins

The gene

Basic information

• Locus tag: BSU02550

Database entries

• BsubCyc: BSU02550

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: OmpR family of two-component response regulators

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation by YcbM ( on an aspartate residue, putative)

• Cofactor(s):

• Effectors of protein activity: activity is controlled by YcbM-dependent phosphorylation (putative)

• Interactions:
  • YcbM-YcbL (putative)

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU02550

• Structure:

• UniProt: P42244

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ycbL-ycbM (according to DBTBS)

• Expression browser: ycbL PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)