YwiE

• Description: minor cardiolipin synthetase, general stress protein, required for protection against paraquat stress
  
  

Gene name	ywiE
Synonyms
Essential	no
Product	minor cardiolipin synthetase
Function	phospholipiid biosynthesis, protection against paraquat stress
Gene expression levels in SubtiExpress: ywiE
Metabolic function and regulation of this protein in SubtiPathways: ywiE
MW, pI	58 kDa, 8.384
Gene length, protein length	1500 bp, 500 aa
Immediate neighbours	ywjA, narI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of lipids, general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress, membrane proteins

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU37240

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 2 Phosphatidylglycerol = diphosphatidylglycerol + glycerol (according to Swiss-Prot)

• Protein family: Cardiolipin synthase subfamily (according to Swiss-Prot)

• Paralogous protein(s): ClsA, YwjE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P45860

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ywiE PubMed

• Sigma factor: SigB PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: