Difference between revisions of "AdaB"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU01820&redirect=T BSU01820] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/adaAB.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/adaAB.html] | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU01820&redirect=T BSU01820] | ||
* '''Structure:''' | * '''Structure:''' | ||
Revision as of 12:52, 2 April 2014
- Description: O6-methylguanine-DNA methyltransferase
| Gene name | adaB |
| Synonyms | |
| Essential | no |
| Product | O6-methylguanine-DNA methyltransferase |
| Function | adaptive response to alkylative DNA damage |
| Gene expression levels in SubtiExpress: adaB | |
| MW, pI | 19 kDa, 6.152 |
| Gene length, protein length | 537 bp, 179 aa |
| Immediate neighbours | adaA, ndhF |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
DNA repair/ recombination, prophage 1
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU01820
Phenotypes of a mutant
Database entries
- BsubCyc: BSU01820
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine (according to Swiss-Prot)
- Protein family: MGMT family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU01820
- Structure:
- UniProt: P19220
- KEGG entry: [3]
- E.C. number: 2.1.1.63
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Justin S Lenhart, Jeremy W Schroeder, Brian W Walsh, Lyle A Simmons
DNA repair and genome maintenance in Bacillus subtilis.
Microbiol Mol Biol Rev: 2012, 76(3);530-64
[PubMed:22933559]
[WorldCat.org]
[DOI]
(I p)
Original publications
F Morohoshi, K Hayashi, N Munakata
Bacillus subtilis ada operon encodes two DNA alkyltransferases.
Nucleic Acids Res: 1990, 18(18);5473-80
[PubMed:2120677]
[WorldCat.org]
[DOI]
(P p)
