CsbC

• Description: general stress protein, similar to pentose transporter
  
  

Gene name	csbC
Synonyms	yxcC
Essential	no
Product	putative pentose transporter
Function	unknown
Gene expression levels in SubtiExpress: csbC
Interactions involving this protein in SubtInteract: CsbC
MW, pI	49 kDa, 9.943
Gene length, protein length	1383 bp, 461 aa
Immediate neighbours	yxcD, htpG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, general stress proteins (controlled by SigB), membrane proteins

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU39810

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): AraE, CsbC, IolT, YfiG, YncC, YwtG

Extended information on the protein

• Kinetic information:

• Domains:
  • contains 12 trans-membrane domains PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • CsbC is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed
  • CsbC-TatAD PubMed
  • CsbC-TatCD PubMed

• Localization:
  • homogeneously distributed in the cell membrane PubMed

Database entries

• Structure:

• UniProt: P46333

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: csbC PubMed

• Sigma factor: SigB PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Carmine G Monteferrante, Calum MacKichan, Elodie Marchadier, Maria-Victoria Prejean, Rut Carballido-López, Jan Maarten van Dijl
Mapping the twin-arginine protein translocation network of Bacillus subtilis.
Proteomics: 2013, 13(5);800-11
[PubMed:23180473] [WorldCat.org] [DOI] (I p)

Elodie Marchadier, Rut Carballido-López, Sophie Brinster, Céline Fabret, Peggy Mervelet, Philippe Bessières, Marie-Françoise Noirot-Gros, Vincent Fromion, Philippe Noirot
An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach.
Proteomics: 2011, 11(15);2981-91
[PubMed:21630458] [WorldCat.org] [DOI] (I p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

Samina Akbar, Soon Youl Lee, Sharon A Boylan, Chester W Price
Two genes from Bacillus subtilis under the sole control of the general stress transcription factor sigmaB.
Microbiology (Reading): 1999, 145 ( Pt 5);1069-1078
[PubMed:10376822] [WorldCat.org] [DOI] (P p)