Difference between revisions of "CmoO"

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m (Jstuelk moved page YtmO to CmoO)
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* '''Description:''' similar to monooxygenase <br/><br/>
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* '''Description:''' monooxygenase, required for the conversion of S-methyl-cysteine to cysteine <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
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|''ytmO''
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|''cmoO''
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ytmO ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
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|style="background:#ABCDEF;" align="center"| '''Product''' || monooxygenase
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
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|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of S-methyl-cysteine
 
|-
 
|-
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29330 ytmO]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29330 cmoO]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/riboflavin.html Riboflavin / FAD]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/riboflavin.html Riboflavin / FAD]'''
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1002 bp, 334 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1002 bp, 334 aa  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytnI]]'', ''[[tcyN]]''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cmoI]]'', ''[[tcyN]]''
 
|-
 
|-
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29330 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29330 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29330 DNA_with_flanks]
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29330 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29330 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29330 DNA_with_flanks]
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<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
−
<br/><br/><br/><br/>
+
<br/><br/>
−
<br/><br/><br/><br/>
 
−
 
 
−
 
 
−
<br/><br/><br/><br/><br/><br/>
 
  
 
= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
−
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}}
+
{{SubtiWiki category|[[sulfur metabolism]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
{{SubtiWiki regulon|[[CymR regulon]]}},
 
{{SubtiWiki regulon|[[CymR regulon]]}},
−
{{SubtiWiki regulon|[[YtlI regulon]]}}
+
{{SubtiWiki regulon|[[AscR regulon]]}}
  
 
=The gene=
 
=The gene=
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* no growth with S-methyl cysteine {{PubMed|23944997}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
−
* '''Interactions:'''
+
* '''[[SubtInteract|Interactions]]:'''
  
−
* '''Localization:'''
+
* '''[[Localization]]:'''
  
 
=== Database entries ===
 
=== Database entries ===
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=Expression and regulation=
 
=Expression and regulation=
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* '''Operon:''' ''[[ytmI]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[ytmO]]-[[ytnI]]-[[ytnJ]]-[[ribR]]-[[ytnL]]-[[ytnM]]'' {{PubMed|15668000}}
+
* '''Operon:''' ''[[snaA]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[cmoO]]-[[cmoI]]-[[cmoJ]]-[[ribR]]-[[sndA]]-[[ytnM]]'' {{PubMed|15668000}}
  
−
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytmO_3003345_3004349_-1 ytmO] {{PubMed|22383849}}
+
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytmO_3003345_3004349_-1 cmoO] {{PubMed|22383849}}
  
−
* '''Sigma factor:''' [[SigA]] {{PubMed|15272571}}
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|15272571}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 
** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}}
 
** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}}
 +
** induced in the presence of S-methyl-cysteine ([[AscR]]) {{PubMed|23944997}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 
** [[CymR]]: transcription repression {{PubMed|16109943}}
 
** [[CymR]]: transcription repression {{PubMed|16109943}}
−
** [[YtlI]]: transcription activation {{PubMed|16109943}}  
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** [[AscR]]: transcription activation {{PubMed|16109943}}  
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
  
−
<pubmed>16109943,15668000, 15272571</pubmed>
+
<pubmed>16109943,15668000, 15272571 23944997</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:28, 18 August 2013

  • Description: monooxygenase, required for the conversion of S-methyl-cysteine to cysteine

Gene name cmoO
Synonyms ytmO
Essential no
Product monooxygenase
Function utilization of S-methyl-cysteine
Gene expression levels in SubtiExpress: cmoO
Metabolic function and regulation of this protein in SubtiPathways:
Riboflavin / FAD
MW, pI 36 kDa, 5.845
Gene length, protein length 1002 bp, 334 aa
Immediate neighbours cmoI, tcyN
Sequences Protein DNA DNA_with_flanks
Genetic context
YtmO context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtmO expression.png















Categories containing this gene/protein

sulfur metabolism

This gene is a member of the following regulons

CymR regulon, AscR regulon

The gene

Basic information

  • Locus tag: BSU29330

Phenotypes of a mutant

  • no growth with S-methyl cysteine PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of cysteine (CymR) PubMed
    • induced in the presence of S-methyl-cysteine (AscR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

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