Difference between revisions of "LmrA"
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| − | * '''Description:''' transcriptional regulator, control of ''[[qdoI]]-[[yxaH]]'' and ''[[lmrA]]-[[lmrB]]'' <br/><br/> | + | * '''Description:''' transcriptional regulator ([[TetR family]]), control of ''[[qdoI]]-[[yxaH]]'' and ''[[lmrA]]-[[lmrB]]'' <br/><br/> |
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| − | * '''Protein family:''' | + | * '''Protein family:''' [[TetR family]] |
* '''Paralogous protein(s):''' [[QdoR]] | * '''Paralogous protein(s):''' [[QdoR]] | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=lmrA_290132_290698_-1 lmrA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=lmrA_290132_290698_-1 lmrA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|12499232}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|12499232}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
| + | ==Reviews== | ||
| + | <pubmed>24006471 </pubmed> | ||
| + | ==Original publications== | ||
<pubmed>15317768,17483215,12499232 , 21815947 </pubmed> | <pubmed>15317768,17483215,12499232 , 21815947 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:30, 6 September 2013
- Description: transcriptional regulator (TetR family), control of qdoI-yxaH and lmrA-lmrB
| Gene name | lmrA |
| Synonyms | lin-2, yccB |
| Essential | no |
| Product | transcriptional regulator |
| Function | regulation of lincomycin resistance |
| Gene expression levels in SubtiExpress: lmrA | |
| MW, pI | 20 kDa, 5.033 |
| Gene length, protein length | 564 bp, 188 aa |
| Immediate neighbours | lmrB, ansZ |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
transcription factors and their control, resistance against toxins/ antibiotics
This gene is a member of the following regulons
The LmrA regulon:
The gene
Basic information
- Locus tag: BSU02680
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: TetR family
- Paralogous protein(s): QdoR
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: flavonoids such as quercetin serve as inducers, binding results in release from DNA PubMed
Database entries
- Structure:
- UniProt: O34619
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Leslie Cuthbertson, Justin R Nodwell
The TetR family of regulators.
Microbiol Mol Biol Rev: 2013, 77(3);440-75
[PubMed:24006471]
[WorldCat.org]
[DOI]
(I p)
Original publications
