Difference between revisions of "MurAB"

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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=murAB_3806086_3807375_-1 murAB] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=murAB_3806086_3807375_-1 murAB] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''Regulation:''' constitutive  [http://www.ncbi.nlm.nih.gov/sites/entrez/19270101 PubMed]
 
* '''Regulation:''' constitutive  [http://www.ncbi.nlm.nih.gov/sites/entrez/19270101 PubMed]
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=References=
 
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== Reviews ==
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<pubmed> 21822642 </pubmed>
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== Original publications ==
 
<pubmed>19270101  </pubmed>
 
<pubmed>19270101  </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:52, 9 September 2013

  • Description: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Gene name murAB
Synonyms murZ, lssF, rev-4
Essential no
Product UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Function peptidoglycan precursor biosynthesis
Gene expression levels in SubtiExpress: murAB
Metabolic function and regulation of this protein in SubtiPathways:
Cell wall
MW, pI 45 kDa, 5.831
Gene length, protein length 1287 bp, 429 aa
Immediate neighbours glpX, ywjH
Sequences Protein DNA DNA_with_flanks
Genetic context
MurAB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MurAB expression.png















Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU37100

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine (according to Swiss-Prot)
  • Protein family: MurA subfamily (according to Swiss-Prot)
  • Paralogous protein(s): MurAA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3SG1 (from B. anthracis, 50% identity, 81% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation: constitutive PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications