Difference between revisions of "ThrC"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | + | {{SubtiWiki regulon|[[CodY regulon]]}} | |
=The gene= | =The gene= | ||
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=== Additional information=== | === Additional information=== | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thrC_3313770_3314828_-1 thrC] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thrC_3313770_3314828_-1 thrC] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
** repressed by casamino acids {{PubMed|12107147}} | ** repressed by casamino acids {{PubMed|12107147}} | ||
| + | ** repressed during growth in the presence of branched chain amino acids ([[CodY]]) {{PubMed|24163341}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | + | ** [[CodY]]: transcription repression {{PubMed|24163341}} | |
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | <pubmed>12107147 3098560, </pubmed> | + | <pubmed>12107147 3098560, 24163341</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 14:06, 22 December 2013
- Description: threonine synthase
| Gene name | thrC |
| Synonyms | thrB |
| Essential | no |
| Product | threonine synthase |
| Function | biosynthesis of threonine |
| Gene expression levels in SubtiExpress: thrC | |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr | |
| MW, pI | 37 kDa, 5.185 |
| Gene length, protein length | 1056 bp, 352 aa |
| Immediate neighbours | thrB, hom |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU32250
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: O-phospho-L-homoserine + H2O = L-threonine + phosphate (according to Swiss-Prot)
- Protein family: serine/threonine dehydratase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- UniProt: P04990
- KEGG entry: [2]
- E.C. number: 4.2.3.1
Additional information
Expression and regulation
- Regulation:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
