RipX

• Description: site-specific integrase/recombinase, partitioning of the terminus region after replication
  
  

Gene name	ripX
Synonyms	ykqM
Essential	no
Product	site-specific integrase/recombinase
Function	chromosome partitioning
Gene expression levels in SubtiExpress: ripX
MW, pI	33 kDa, 10
Gene length, protein length	888 bp, 296 aa
Immediate neighbours	drm, yqzK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA condensation/ segregation

The gene

Basic information

• Locus tag: BSU23510

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: resolution of chromosome dimers by site specific recombination at the dif site (located close to the terminus region on the chromosome)

• Protein family: XerD subfamily (according to Swiss-Prot)

• Paralogous protein(s): CodV

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)
  • assembles on the chromosome at the dif site throughout the cell cycle PubMed

Database entries

• Structure:

• UniProt: P46352

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ripX PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A793 ( ripX::spec), PubMed, available at BGSC
  • 1A796 ( ripX::spec), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Xindan Wang, Paula Montero Llopis, David Z Rudner
Organization and segregation of bacterial chromosomes.
Nat Rev Genet: 2013, 14(3);191-203
[PubMed:23400100] [WorldCat.org] [DOI] (I p)