AdeC

• Description: adenine deaminase
  
  

Gene name	adeC
Synonyms	ade, yzaD
Essential	no
Product	adenine deaminase
Function	utilization of adenine as nitrogen source, purine salvage and interconversion
Gene expression levels in SubtiExpress: adeC
Metabolic function and regulation of this protein in SubtiPathways: adeC
MW, pI	62 kDa, 4.724
Gene length, protein length	1731 bp, 577 aa
Immediate neighbours	ktrC, rnjA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of nucleotides

The gene

Basic information

• Locus tag: BSU14520

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Adenine + H₂O = hypoxanthine + NH₃ (according to Swiss-Prot)

• Protein family: adenine deaminase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39761

• KEGG entry: [2]

• E.C. number: 3.5.4.2

Expression and regulation

• Operon:

• Expression browser: adeC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

P Nygaard, P Duckert, H H Saxild
Role of adenine deaminase in purine salvage and nitrogen metabolism and characterization of the ade gene in Bacillus subtilis.
J Bacteriol: 1996, 178(3);846-53
[PubMed:8550522] [WorldCat.org] [DOI] (P p)