Difference between revisions of "SasB"

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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* a ''[[relA]] [[yjbM]] [[ywaC]]'' triple mutant requires branched chain amino acids, methionine and threonine for growth, the requirement can be suppressed by reduced expression of ''[[guaB]]'' or inactivation of ''[[codY]]'' {{PubMed|24163341}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:''' single ppGpp synthetase domain {{PubMed|24163341}}
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yjbM_1237006_1237641_1 yjbM] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yjbM_1237006_1237641_1 yjbM] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:''' expressed during exponential growth
 
* '''Regulation:''' expressed during exponential growth
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=References=
 
=References=
'''Additional publications:''' {{PubMed|22950019}}
+
<pubmed>22950019 18670626 19447912 18067544 24163341</pubmed>
<pubmed> 18670626 19447912 18067544 </pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:46, 22 December 2013

  • Description: (p)ppGpp synthetase

Gene name yjbM
Synonyms
Essential no
Product (p)ppGpp synthetase
Function ppGpp synthesis independent from stringent response
Gene expression levels in SubtiExpress: yjbM
MW, pI 24 kDa, 6.708
Gene length, protein length 633 bp, 211 aa
Immediate neighbours yjbL, nadF
Sequences Protein DNA DNA_with_flanks
Genetic context
YjbM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YjbM expression.png















Categories containing this gene/protein

metabolism of signalling nucleotides

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU11600

Phenotypes of a mutant

  • a relA yjbM ywaC triple mutant requires branched chain amino acids, methionine and threonine for growth, the requirement can be suppressed by reduced expression of guaB or inactivation of codY PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): YwaC

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed during exponential growth
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References