Difference between revisions of "TrpP"

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* '''Description:''' L-tryptophan transporter (proton symport) <br/><br/>
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* '''Description:''' S protein of tryptophan [[ECF transporter]] <br/><br/>
 
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
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|style="background:#ABCDEF;" align="center"| '''Product''' || L-tryptophan transporter (proton symport)
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|style="background:#ABCDEF;" align="center"| '''Product''' || S protein of tryptophan [[ECF transporter]]
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || tryptophan uptake
 
|style="background:#ABCDEF;" align="center"|'''Function''' || tryptophan uptake
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<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
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<br/><br/>
<br/><br/><br/><br/>
 
 
 
 
 
<br/><br/><br/><br/><br/><br/>
 
  
 
= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
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{{SubtiWiki category|[[ECF transporter]]}},
 
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
 
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
 
{{SubtiWiki category|[[membrane proteins]]}}
 
{{SubtiWiki category|[[membrane proteins]]}}
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=trpP_1074646_1075164_-1 trpP] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=trpP_1074646_1075164_-1 trpP] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] {{PubMed|10735881}}  
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* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|10735881}}  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 15:13, 13 July 2013

Gene name trpP
Synonyms yhaG
Essential no
Product S protein of tryptophan ECF transporter
Function tryptophan uptake
Gene expression levels in SubtiExpress: trpP
Metabolic function and regulation of this protein in SubtiPathways:
Phe, Tyr, Trp
MW, pI 18 kDa, 11.155
Gene length, protein length 516 bp, 172 aa
Immediate neighbours yhzF, serC
Sequences Protein DNA DNA_with_flanks
Genetic context
YhaG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TrpP expression.png















Categories containing this gene/protein

ECF transporter, biosynthesis/ acquisition of amino acids, membrane proteins

This gene is a member of the following regulons

TRAP regulon

The gene

Basic information

  • Locus tag: BSU10010

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: trpP transporter family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced in the absence of tryptophan (MtrB) PubMed
  • Regulatory mechanism:
    • MtrB: translation inhibition at an RNA switch, the MtrB binding site overlaps the Shine-DAlgarno sequence and translation initation region, MtrB binds in the presence of tryptophan PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References