Difference between revisions of "CotP"
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| − | * '''Description:''' | + | * '''Description:''' inner spore coat protein <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || inner spore coat protein |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance of the spore | |style="background:#ABCDEF;" align="center"|'''Function''' || resistance of the spore | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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| − | |||
| − | |||
| − | |||
<br/><br/> | <br/><br/> | ||
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[GerE regulon]]}}, | ||
{{SubtiWiki regulon|[[SigK regulon]]}} | {{SubtiWiki regulon|[[SigK regulon]]}} | ||
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=== Additional information=== | === Additional information=== | ||
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* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| + | ** inner spore coat, localization depends on [[SafA]] {{PubMed|22171814}} | ||
=== Database entries === | === Database entries === | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed during sporulation ([[SigK]] | + | ** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|15699190,9068633}} |
| − | |||
| − | * '''Regulatory mechanism:''' | + | * '''Regulatory mechanism:''' |
| + | ** [[GerE]]: transcription repression {{PubMed|9068633}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 139: | Line 135: | ||
=References= | =References= | ||
| − | <pubmed>11150673,15699190, 9068633</pubmed> | + | <pubmed>11150673,15699190, 9068633 22171814</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:34, 13 August 2013
- Description: inner spore coat protein
| Gene name | cotP |
| Synonyms | ydfT |
| Essential | no |
| Product | inner spore coat protein |
| Function | resistance of the spore |
| Gene expression levels in SubtiExpress: cotP | |
| MW, pI | 16 kDa, 4.56 |
| Gene length, protein length | 429 bp, 143 aa |
| Immediate neighbours | ydfS, ydgA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU05550
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: small heat shock protein (HSP20) family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P96698
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814]
[WorldCat.org]
[DOI]
(I p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
S Reischl, S Thake, G Homuth, W Schumann
Transcriptional analysis of three Bacillus subtilis genes coding for proteins with the alpha-crystallin domain characteristic of small heat shock proteins.
FEMS Microbiol Lett: 2001, 194(1);99-103
[PubMed:11150673]
[WorldCat.org]
[DOI]
(P p)
A O Henriques, B W Beall, C P Moran
CotM of Bacillus subtilis, a member of the alpha-crystallin family of stress proteins, is induced during development and participates in spore outer coat formation.
J Bacteriol: 1997, 179(6);1887-97
[PubMed:9068633]
[WorldCat.org]
[DOI]
(P p)
