Difference between revisions of "GamA"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[YbgR regulon]]}} | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * no growth on glucosamine {{PubMed|23667565}} | ||
=== Database entries === | === Database entries === | ||
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=References= | =References= | ||
| − | <pubmed>10627040, 14343123 </pubmed> | + | <pubmed>10627040, 14343123 23667565</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:25, 24 May 2013
- Description: glucosamine-6-phosphate deaminase
| Gene name | gamA |
| Synonyms | ybfT |
| Essential | no |
| Product | glucosamine-6-phosphate deaminase |
| Function | glucosamine utilization |
| Gene expression levels in SubtiExpress: gamA | |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 27 kDa, 5.793 |
| Gene length, protein length | 747 bp, 249 aa |
| Immediate neighbours | gamP, ybgA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall degradation/ turnover, utilization of specific carbon sources
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU02360
Phenotypes of a mutant
- no growth on glucosamine PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: d-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3 (according to Swiss-Prot)
- Protein family: NagB subfamily (according to Swiss-Prot)
- Paralogous protein(s): NagB
Extended information on the protein
- Kinetic information: K(M): 3.0 mM PubMed
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31458
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- induced by N-acetylglucosamine PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Isabelle Gaugué, Jacques Oberto, Harald Putzer, Jacqueline Plumbridge
The use of amino sugars by Bacillus subtilis: presence of a unique operon for the catabolism of glucosamine.
PLoS One: 2013, 8(5);e63025
[PubMed:23667565]
[WorldCat.org]
[DOI]
(I e)
Jonathan Reizer, Steffi Bachem, Aiala Reizer, Maryvonne Arnaud, Milton H Saier, Jörg Stülke
Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 12);3419-3429
[PubMed:10627040]
[WorldCat.org]
[DOI]
(P p)
C J BATES, C A PASTERNAK
FURTHER STUDIES ON THE REGULATION OF AMINO SUGAR METABOLISM IN BACILLUS SUBTILIS.
Biochem J: 1965, 96(1);147-54
[PubMed:14343123]
[WorldCat.org]
[DOI]
(P p)
