YydI

• Description: ABC transporter (resistance), ATP-binding protein, export of YydF
  
  

Gene name	yydI
Synonyms
Essential	no
Product	ABC transporter (resistance), ATP-binding protein
Function	control of LiaR-LiaS activity
Gene expression levels in SubtiExpress: yydI
Interactions involving this protein in SubtInteract: YydI
MW, pI	23 kDa, 8.387
Gene length, protein length	627 bp, 209 aa
Immediate neighbours	yydJ, yydH
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, transcription factors and their control, membrane proteins

This gene is a member of the following regulons

AbrB regulon, Rok regulon

The gene

Basic information

• Locus tag: BSU40150

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YydI-(YydJ-YydH) PubMed

• Localization: membrane associated (via YydJ-YydH) PubMed

Database entries

• Structure:

• UniProt: Q45593

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yydF-yydG-yydH-yydI-yydJ PubMed

• Expression browser: yydI PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • activated after transition to stationary phase(AbrB) PubMed
  • repressed by Rok PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed
  • Rok: transcription repression PubMed

• Additional information:
  • the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Susanne Gebhard
ABC transporters of antimicrobial peptides in Firmicutes bacteria - phylogeny, function and regulation.
Mol Microbiol: 2012, 86(6);1295-317
[PubMed:23106164] [WorldCat.org] [DOI] (I p)

Original publications

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947