LicR

• Description: transcriptional activator of the licB-licC-licA-licH operon
  
  

Gene name	licR
Synonyms	celR
Essential	no
Product	transcriptional activator, PRD-type
Function	regulation of lichenan utilization
Gene expression levels in SubtiExpress: licR
Interactions involving this protein in SubtInteract: LicR
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	73 kDa, 6.115
Gene length, protein length	1923 bp, 641 aa
Immediate neighbours	licB, yxzF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control, phosphoproteins

The LicR regulon:

• licB-licC-licA-licH

The gene

Basic information

• Locus tag: BSU38600

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)

• Protein family: transcriptional antiterminator bglG family (according to Swiss-Prot), Attention: this is wrong: LicR is a transcription activator, the similarity to the BglG family is limited to the PTS-regulation domains

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • LicB-LicR
  • PtsH-LicR

• Localization:

Database entries

• Structure:

• UniProt: P46321

• KEGG entry: [3]

• E.C. number: 2.7.1.69

Expression and regulation

• Operon: licR PubMed

• Expression browser: licR PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: