Difference between revisions of "RsbP"
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Revision as of 14:36, 16 May 2013
- Description: protein serine phosphatase, energy PP2C, dephosphorylates RsbV
Gene name | rsbP |
Synonyms | yvfP |
Essential | no |
Product | protein serine phosphatase, energy PP2C |
Function | control of SigB activity |
Gene expression levels in SubtiExpress: rsbP | |
Interactions involving this protein in SubtInteract: RsbP | |
Metabolic function and regulation of this protein in SubtiPathways: Stress | |
MW, pI | 45 kDa, 4.827 |
Gene length, protein length | 1209 bp, 403 aa |
Immediate neighbours | rsbQ, ganB |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
protein modification, sigma factors and their control
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU34110
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: dephosphorylation of RsbV in response to red light, this results in SigB activation PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: N-terminal PAS domain, central coiled-coil domain, C-terminal PP2C phosphatase domain
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- activity is stimulated upon interaction of the RsbP oligomer with RsbQ PubMed
Database entries
- Structure:
- UniProt: O07014
- KEGG entry: [2]
- E.C. number: 3.1.3.3
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Chet Price, Davis, USA homepage
Your additional remarks
References
Reviews
Jon Marles-Wright, Richard J Lewis
The stressosome: molecular architecture of a signalling hub.
Biochem Soc Trans: 2010, 38(4);928-33
[PubMed:20658979]
[WorldCat.org]
[DOI]
(I p)
Original publications
Additional publications: PubMed
Locke JC, Young JW, Fontes M, Hernández Jiménez MJ, Elowitz MB Stochastic pulse regulation in bacterial stress response. Science. 2011 334:366-369. PubMed:21979936