Difference between revisions of "YvrI"
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Revision as of 14:32, 16 May 2013
- Description: RNA polymerase sigma factor YvrI
| Gene name | yvrI |
| Synonyms | sigO |
| Essential | no |
| Product | co-sigma factor with YvrHa |
| Function | RNA polymerase sigma factor |
| Gene expression levels in SubtiExpress: yvrI | |
| Interactions involving this protein in SubtInteract: YvrI | |
| MW, pI | 20.76 kDa, 9.36 |
| Gene length, protein length | 531 bp, 176 aa |
| Immediate neighbours | yvrHa, yvrJ |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription, sigma factors and their control, acid stress proteins (controlled by YvrI-YvrHa)
This gene is a member of the following regulons
YvrHb regulon, YvrI-YvrHa regulon
The YvrI-YvrHa regulon
The gene
Basic information
- Locus tag: BSU33230
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: contains a DNA-binding helix-turn-helix motif (HTH) and the region 4.2 of Sigma factors PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34843
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: induced by acidic growth conditions PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
Your additional remarks
References
Shawn R MacLellan, Veronica Guariglia-Oropeza, Ahmed Gaballa, John D Helmann
A two-subunit bacterial sigma-factor activates transcription in Bacillus subtilis.
Proc Natl Acad Sci U S A: 2009, 106(50);21323-8
[PubMed:19940246]
[WorldCat.org]
[DOI]
(I p)
Shawn R MacLellan, John D Helmann, Haike Antelmann
The YvrI alternative sigma factor is essential for acid stress induction of oxalate decarboxylase in Bacillus subtilis.
J Bacteriol: 2009, 191(3);931-9
[PubMed:19047353]
[WorldCat.org]
[DOI]
(I p)
Shawn R MacLellan, Tina Wecke, John D Helmann
A previously unidentified sigma factor and two accessory proteins regulate oxalate decarboxylase expression in Bacillus subtilis.
Mol Microbiol: 2008, 69(4);954-67
[PubMed:18573182]
[WorldCat.org]
[DOI]
(I p)
Masakuni Serizawa, Keisuke Kodama, Hiroki Yamamoto, Kazuo Kobayashi, Naotake Ogasawara, Junichi Sekiguchi
Functional analysis of the YvrGHb two-component system of Bacillus subtilis: identification of the regulated genes by DNA microarray and northern blot analyses.
Biosci Biotechnol Biochem: 2005, 69(11);2155-69
[PubMed:16306698]
[WorldCat.org]
[DOI]
(P p)
