Difference between revisions of "YrvM"
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Revision as of 14:06, 16 May 2013
- Description: similar to E. coli enzyme that catalyzes ATP-dependent dehydration of N6-threonylcarbamoyladenosine (t6A) to form cyclic N6-threonylcarbamoyladenosine (ct6A)
| Gene name | yrvM |
| Synonyms | |
| Essential | no |
| Product | N6-threonylcarbamoyladenosine cyclase |
| Function | tRNA modification |
| Gene expression levels in SubtiExpress: yrvM | |
| MW, pI | 28 kDa, 8.187 |
| Gene length, protein length | 762 bp, 254 aa |
| Immediate neighbours | yrvN, bsrA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27540
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- catalyzes ATP-dependent dehydration of N6-threonylcarbamoyladenosine (t6A) to form cyclic N6-threonylcarbamoyladenosine (ct6A) (ct6A recognizes the first adenine base of ANN codon at the ribosomal A site) PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O32037
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kenjyo Miyauchi, Satoshi Kimura, Tsutomu Suzuki
A cyclic form of N6-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification.
Nat Chem Biol: 2013, 9(2);105-11
[PubMed:23242255]
[WorldCat.org]
[DOI]
(I p)
