Difference between revisions of "GcvPA"
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Revision as of 13:53, 16 May 2013
- Description: glycine decarboxylase (subunit 1)
| Gene name | gcvPA |
| Synonyms | yqhJ, gcvP |
| Essential | no |
| Product | glycine decarboxylase (subunit 1) |
| Function | glycine utilization |
| Gene expression levels in SubtiExpress: gcvPA | |
| MW, pI | 49 kDa, 6.947 |
| Gene length, protein length | 1344 bp, 448 aa |
| Immediate neighbours | gcvPB, gcvT |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24560
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2 (according to Swiss-Prot)
- Protein family: N-terminal subunit subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P54376
- KEGG entry: [3]
- E.C. number: 1.4.4.2
Additional information
Expression and regulation
- Sigma factor:
- Regulatory mechanism:
- induction requires a co-operatively acting riboswitch (Gly-box) PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Maumita Mandal, Mark Lee, Jeffrey E Barrick, Zasha Weinberg, Gail Mitchell Emilsson, Walter L Ruzzo, Ronald R Breaker
A glycine-dependent riboswitch that uses cooperative binding to control gene expression.
Science: 2004, 306(5694);275-9
[PubMed:15472076]
[WorldCat.org]
[DOI]
(I p)
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
