Difference between revisions of "LonB"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lonA]]'', ''[[clpX]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lonA]]'', ''[[clpX]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28210 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28210 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28210 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28210 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28210 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28210 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:lonB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:lonB_context.gif]]

Revision as of 10:55, 14 May 2013

  • Description: Lon-like ATP-dependent protease

Gene name lonB
Synonyms ysxF
Essential no
Product Lon-like ATP-dependent protease
Function protein quality control
Gene expression levels in SubtiExpress: lonB
MW, pI 60 kDa, 6.272
Gene length, protein length 1656 bp, 552 aa
Immediate neighbours lonA, clpX
Sequences Protein DNA DNA_with_flanks
Genetic context
LonB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LonB expression.png















Categories containing this gene/protein

proteolysis, sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigF regulon

The gene

Basic information

  • Locus tag: BSU28210

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase S16 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Localization:
    • localized to the forespore membrane early in development, followed by localization throughout the forespore later in development PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the forespore (SigF) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Additional reviews: PubMed

Original publications

Lyle A Simmons, Alan D Grossman, Graham C Walker
Clp and Lon proteases occupy distinct subcellular positions in Bacillus subtilis.
J Bacteriol: 2008, 190(20);6758-68
[PubMed:18689473] [WorldCat.org] [DOI] (I p)

Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325] [WorldCat.org] [DOI] (P p)

M Serrano, S Hövel, C P Moran, A O Henriques, U Völker
Forespore-specific transcription of the lonB gene during sporulation in Bacillus subtilis.
J Bacteriol: 2001, 183(10);2995-3003
[PubMed:11325926] [WorldCat.org] [DOI] (P p)

E Krüger, M Hecker
The first gene of the Bacillus subtilis clpC operon, ctsR, encodes a negative regulator of its own operon and other class III heat shock genes.
J Bacteriol: 1998, 180(24);6681-8
[PubMed:9852015] [WorldCat.org] [DOI] (P p)