Difference between revisions of "NrgB"

From SubtiWiki
Jump to: navigation, search
Line 14: Line 14:
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of ammonium uptake  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of ammonium uptake  
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU36520 nrgB]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36520 nrgB]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/NrgB NrgB]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/NrgB NrgB]

Revision as of 14:03, 13 May 2013

  • Description: nitrogen-regulated PII-like protein

Gene name nrgB
Synonyms glnK
Essential no
Product nitrogen-regulated PII-like protein
Function regulation of ammonium uptake
Gene expression levels in SubtiExpress: nrgB
Interactions involving this protein in SubtInteract: NrgB
Metabolic function and regulation of this protein in SubtiPathways:
Ammonium/ glutamate
MW, pI 12 kDa, 8.825
Gene length, protein length 348 bp, 116 aa
Immediate neighbours nrgA, bcrC
Gene sequence (+200bp) Protein sequence
Genetic context
NrgB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NrgB expression.png















Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, glutamate metabolism, transcription factors and their control, membrane proteins

This gene is a member of the following regulons

TnrA regulon

The gene

Basic information

  • Locus tag: BSU36520

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: P(II) protein family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: induced by ammonium limitation
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: GP259 (cat), GP255 (nrgAB, cat), both available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:

Labs working on this gene/protein

Susan Fisher, Boston, USA homepage

Your additional remarks

References

Reviews

Karl Forchhammer
P(II) signal transducers: novel functional and structural insights.
Trends Microbiol: 2008, 16(2);65-72
[PubMed:18182294] [WorldCat.org] [DOI] (P p)

T Arcondéguy, R Jack, M Merrick
P(II) signal transduction proteins, pivotal players in microbial nitrogen control.
Microbiol Mol Biol Rev: 2001, 65(1);80-105
[PubMed:11238986] [WorldCat.org] [DOI] (P p)

G Thomas, G Coutts, M Merrick
The glnKamtB operon. A conserved gene pair in prokaryotes.
Trends Genet: 2000, 16(1);11-4
[PubMed:10637624] [WorldCat.org] [DOI] (P p)

Original publications

Additional publications: PubMed