Difference between revisions of "YofA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of ''[[ftsW]]'' expression | |style="background:#ABCDEF;" align="center"|'''Function''' || control of ''[[ftsW]]'' expression | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18420 yofA] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 6.164 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 6.164 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ggt]]'', ''[[yogA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ggt]]'', ''[[yogA]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU18420 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU18420 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU18420 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yofA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yofA_context.gif]] | ||
Revision as of 12:58, 13 May 2013
- Description: transcriptional activator of ftsW at the onset of stationary phase
| Gene name | yofA |
| Synonyms | ftsR |
| Essential | no |
| Product | transcriptional activator (LysR family) |
| Function | control of ftsW expression |
| Gene expression levels in SubtiExpress: yofA | |
| MW, pI | 31 kDa, 6.164 |
| Gene length, protein length | 855 bp, 285 aa |
| Immediate neighbours | ggt, yogA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription factors and their control
This gene is a member of the following regulons
The YofA regulon:
The gene
Basic information
- Locus tag: BSU18420
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: LysR family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- secreted (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O34685
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- maximally expressed at the onset of stationary phase PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849]
[WorldCat.org]
[DOI]
(I p)
Zuolei Lu, Michio Takeuchi, Tsutomu Sato
The LysR-type transcriptional regulator YofA controls cell division through the regulation of expression of ftsW in Bacillus subtilis.
J Bacteriol: 2007, 189(15);5642-51
[PubMed:17526699]
[WorldCat.org]
[DOI]
(P p)
