Difference between revisions of "AdhA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || response to toxic formaldehyde | |style="background:#ABCDEF;" align="center"|'''Function''' || response to toxic formaldehyde | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27010 adhA] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 37 kDa, 5.367 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 37 kDa, 5.367 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrzP]]'', ''[[yraA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrzP]]'', ''[[yraA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27010 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27010 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27010 Advanced_DNA] |
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Revision as of 13:25, 13 May 2013
- Description: thiol-dependent aldehyde dehydrogenase, repair of damaged thiol-containing proteins
| Gene name | adhA |
| Synonyms | |
| Essential | no |
| Product | thiol-dependent aldehyde dehydrogenase, reduction of aldehydes |
| Function | response to toxic formaldehyde |
| Gene expression levels in SubtiExpress: adhA | |
| MW, pI | 37 kDa, 5.367 |
| Gene length, protein length | 1047 bp, 349 aa |
| Immediate neighbours | yrzP, yraA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27010
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: C0SPA5
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Thi Thu Huyen Nguyen, Warawan Eiamphungporn, Ulrike Mäder, Manuel Liebeke, Michael Lalk, Michael Hecker, John D Helmann, Haike Antelmann
Genome-wide responses to carbonyl electrophiles in Bacillus subtilis: control of the thiol-dependent formaldehyde dehydrogenase AdhA and cysteine proteinase YraA by the MerR-family regulator YraB (AdhR).
Mol Microbiol: 2009, 71(4);876-94
[PubMed:19170879]
[WorldCat.org]
[DOI]
(I p)
