Difference between revisions of "TepA"

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* '''Description:''' signal peptide peptidase required for efficient processing of pre-proteins <br/><br/>
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* '''Description:''' [[sporulation]] protein, signal peptide peptidase required for efficient processing of pre-proteins <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
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{{SubtiWiki regulon|[[SigG regulon]]}}
  
 
=The gene=
 
=The gene=
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
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* '''Operon:''' ''[[tepA]]-[[ylzJ]]'' {{PubMed|22383849}}
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tepA_1751201_1751938_1 tepA] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tepA_1751201_1751938_1 tepA] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''Sigma factor:''' [[SigG]] {{PubMed|23123912}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** expressed late during [[sporulation]] in the forespore ([[SigG]]) {{PubMed|23123912}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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=References=
 
=References=
<pubmed>23123912</pubmed>
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<pubmed>23123912 22383849</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:39, 12 November 2012

  • Description: sporulation protein, signal peptide peptidase required for efficient processing of pre-proteins

Gene name tepA
Synonyms ymfB, ylxI
Essential no
Product signal peptide peptidase
Function protein secretion
Gene expression levels in SubtiExpress: tepA
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 24 kDa, 5.575
Gene length, protein length 669 bp, 223 aa
Immediate neighbours rnjB, spoIIIE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TepA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TepA expression.png















Categories containing this gene/protein

protein secretion

This gene is a member of the following regulons

SigG regulon

The gene

Basic information

  • Locus tag: BSU16790

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: TepA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: GP1120 (spc), available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References